Where should neuroblastoma mass screening go?
نویسنده
چکیده
surgical resection of the tumour. Histology of these tumours has revealed ganglioneuroma or ganglioneuroblastoma with scanty foci of neuroblasts. At a recent meeting to reevaluate the screening programme, the consensus was that this attempt at conservative management for carefully selected patients was acceptable but still experimental and it was not recommended for routine use. Conservative treatment is very stressful both for the families and health staff because there is no way of distinguishing those tumours that carry a poor prognosis from spontaneously regressing ones. Legal repercussions can also be expected. This stressful effort at conservative management may help extend knowledge or confirm what is known about the nature of neuroblastomas detected on screening, but it is unlikely to give us the further information required for decision making. The conservative approach may be the best choice to prevent harm to young children in the prevailing situation, but calling a halt to the national screening programme is a better option.
منابع مشابه
Neuroblastoma of the urinary bladder, preclinically detected by mass screening.
BACKGROUND Since the introduction of mass screening of infants for neuroblastoma, the incidence of neuroblastoma has increased in Japan. The reason for this increased incidence is the possible inclusion of many neuroblastomas that would have regressed spontaneously and would never have been detected clinically. An extremely rare tumor at the dome of the urinary bladder in a 7-month-old infant w...
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BACKGROUND/PURPOSE Since 1985, a nationwide mass screening program (MS) for neuroblastoma has been conducted for 6-month-old infants throughout Japan, resulting in the detection of more than 1,900 cases of neuroblastoma. The outcome of these patients has been excellent: more than 97% of them are alive. Yet, several reports suggest that the number of advanced-stage neuroblastoma patients over 1 ...
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ورودعنوان ژورنال:
- Lancet
دوره 348 9043 شماره
صفحات -
تاریخ انتشار 1996